Aurora A Antikörper (AA 93-120)
Kurzübersicht für Aurora A Antikörper (AA 93-120) (ABIN3030070)
Target
Alle Aurora A (AURKA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 93-120
-
Verwendungszweck
- Aurka Antibody
-
Aufreinigung
- Antigen affinity
-
Immunogen
- A portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the Aurka antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Aurka antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
-
Andere Bezeichnung
- Aurka
-
Hintergrund
- Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.
-
UniProt
- P97477
-
Pathways
- Zellzyklus, Asymmetric Protein Localization
Target
-