ATG13 Antikörper (AA 1-30)

Produktnummer ABIN3030086

Produktdetails anti-ATG13 Antikörper

Target: ATG13 (Autophagy Related 13 (ATG13))

Bindungsspezifität: AA 1-30

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Expected species reactivity: Bovine

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this ATG13 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ATG13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ATG13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ATG13

Target: ATG13 (Autophagy Related 13 (ATG13))

Andere Bezeichnung: ATG13 (ATG13 Produkte)

Hintergrund: ATG13 is an autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. [UniProt]

UniProt: O75143

Pathways: PI3K-Akt Signalweg, Autophagie