SIRT1 Antikörper (AA 587-621)
Kurzübersicht für SIRT1 Antikörper (AA 587-621) (ABIN3029010)
Target
Alle SIRT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 587-621
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This anti-SIRT1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 587-621 amino acids from the C-terminal region of human SIRT1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the anti-SIRT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the anti-SIRT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SIRT1 (Sirtuin 1 (SIRT1))
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Andere Bezeichnung
- SIRT1
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Hintergrund
- A NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy.
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UniProt
- Q96EB6
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Pathways
- MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
Target
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