Androgen Receptor Antikörper (AA 365-392)
Kurzübersicht für Androgen Receptor Antikörper (AA 365-392) (ABIN3029940)
Target
Alle Androgen Receptor (AR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 365-392
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Kreuzreaktivität (Details)
- Expected species reactivity: Pig, Primate
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 365-392 from the human protein was used as the immunogen for this Androgen Receptor antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Androgen Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Androgen Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Androgen Receptor (AR)
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Andere Bezeichnung
- Androgen Receptor
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Hintergrund
- Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity of Androgen Receptor is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. [UniProt]
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UniProt
- P10275
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Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
Target
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