ADAM17 Antikörper (AA 195-224)
Kurzübersicht für ADAM17 Antikörper (AA 195-224) (ABIN3029858)
Target
Alle ADAM17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 195-224
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Verwendungszweck
- ADAM17 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 195-224 from the human protein was used as the immunogen for this ADAM17 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the ADAM17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the ADAM17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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Andere Bezeichnung
- ADAM17
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Hintergrund
- ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.
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UniProt
- P78536
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Pathways
- Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus
Target
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