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ADAM17 Antikörper (C-Term)

KO Validated ADAM17 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855021
  • Target Alle ADAM17 Antikörper anzeigen
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Bindungsspezifität
    • 16
    • 13
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 109
    • 54
    • 52
    • 4
    • 4
    • 4
    • 1
    • 1
    Human
    Wirt
    • 94
    • 13
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 86
    • 25
    Polyklonal
    Konjugat
    • 53
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADAM17 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 48
    • 40
    • 15
    • 14
    • 14
    • 12
    • 10
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to ADAM17 (ADAM metallopeptidase domain 17)
    ADAM17 antibody [C2C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human ADAM17. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ADAM17 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: K562 , Raw264.7 , Rat2 , HeLa

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.21 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Andere Bezeichnung
    ADAM metallopeptidase domain 17 (ADAM17 Produkte)
    Synonyme
    ADAM18 antikoerper, CD156B antikoerper, CSVP antikoerper, NISBD antikoerper, TACE antikoerper, CD156b antikoerper, Tace antikoerper, adam17 antikoerper, si:dkey-81b15.2 antikoerper, adam18 antikoerper, cd156b antikoerper, csvp antikoerper, tace antikoerper, fc20b01 antikoerper, wu:fc20b01 antikoerper, zgc:63886 antikoerper, ADAM metallopeptidase domain 17 antikoerper, a disintegrin and metallopeptidase domain 17 antikoerper, ADAM metallopeptidase domain 17b antikoerper, ADAM metallopeptidase domain 17 L homeolog antikoerper, ADAM metallopeptidase domain 17a antikoerper, ADAM17 antikoerper, Adam17 antikoerper, adam17b antikoerper, adam17.L antikoerper, adam17a antikoerper
    Hintergrund
    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

    Cellular Localization: Membrane
    Molekulargewicht
    93 kDa
    Gen-ID
    6868
    UniProt
    P78536
    Pathways
    Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus
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