ABL1 Antikörper (AA 231-260)
Kurzübersicht für ABL1 Antikörper (AA 231-260) (ABIN3030215)
Target
Alle ABL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 231-260
-
Kreuzreaktivität (Details)
- Expected species reactivity: Mouse
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 231-260 from the human protein was used as the immunogen for this ABL1 antibody.
-
Isotyp
- IgG
-
-
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 490-590) antibody
ABL1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr251) antibodyABL1 Reaktivität: Human WB, IF, IHC (p), DB Wirt: Kaninchen Polyclonal RB7351 unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibodyABL1 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr393), (pTyr412) antibodyABL1 Reaktivität: Human, Maus, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 Reaktivität: Human, Maus, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 741-769) antibodyABL1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 741-769) antibodyABL1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB15710 unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibodyABL1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7349 unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr134) antibodyABL1 Reaktivität: Human IHC (p), DB Wirt: Kaninchen Polyclonal RB7343 unconjugated
-
-
Applikationshinweise
- Titration of the ABL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the ABL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
-
Andere Bezeichnung
- ABL1
-
Hintergrund
- The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
-
UniProt
- P00519
-
Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
Target
-
