PINK1 Antikörper (AA 118-147)

Produktnummer ABIN3032405

Der Kaninchen Polyklonal Anti-PINK1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, PINK1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PINK1 Antikörper (AA 118-147) (ABIN3032405)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PINK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PINK1 Antikörper

Bindungsspezifität: AA 118-147

Aufreinigung: Purified

Immunogen: A portion of amino acids 118-147 from the human protein was used as the immunogen for this PINK1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Andere Bezeichnung: PINK1

Hintergrund: Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.

UniProt: Q9BXM7

Pathways: Autophagie