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PDGFRB Antikörper (AA 40-72)

Dieses Anti-PDGFRB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDGFRB in WB, ELISA, IHC, IF und FACS. Geeignet für Human.
Produktnummer ABIN3029811

Kurzübersicht für PDGFRB Antikörper (AA 40-72) (ABIN3029811)

Target

Alle PDGFRB Antikörper anzeigen
PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reaktivität

  • 212
  • 92
  • 71
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 180
  • 42
  • 6
  • 3
  • 1
Kaninchen

Klonalität

  • 164
  • 68
Polyklonal

Konjugat

  • 123
  • 11
  • 8
  • 8
  • 7
  • 6
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
Dieser PDGFRB Antikörper ist unkonjugiert

Applikation

  • 163
  • 73
  • 58
  • 54
  • 53
  • 30
  • 28
  • 27
  • 22
  • 20
  • 16
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 28
    • 22
    • 19
    • 16
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-72

    Aufreinigung

    Purified

    Immunogen

    A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    The stated application concentrations are suggested starting amounts. Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at 4°C for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

    Andere Bezeichnung

    PDGFR beta (CD140b)

    Hintergrund

    PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.

    UniProt

    P09619

    Pathways

    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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