Topoisomerase II alpha Antikörper (AA 1352-1493)
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- Target Alle Topoisomerase II alpha (TOP2A) Antikörper anzeigen
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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Bindungsspezifität
- AA 1352-1493
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Topoisomerase II alpha Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- Amino acids 1352-1493 from the human protein were used as the immunogen for this Topoisomerase II alpha antibody.
- Klon
- TOP2A-1361
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product TOP2A Primärantikörper
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anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) antibody
TOP2A Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1435-1531) antibodyTOP2A Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E2 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1100-1530) antibodyTOP2A Reaktivität: Human WB, ELISA, FACS, ICC Wirt: Maus Monoclonal 6C12G12 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1352-1493) antibodyTOP2A Reaktivität: Human, Maus WB, IHC, IF, StM Wirt: Maus Monoclonal TOP2A-1361 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1100-1530) antibodyTOP2A Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 6D4B2 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1167-1196), (C-Term) antibodyTOP2A Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB24346 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (Internal Region) antibodyTOP2A Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (N-Term) antibodyTOP2A Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (C-Term) antibodyTOP2A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (Thr1343) antibodyTOP2A Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Topoisomerase II alpha antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the Topoisomerase II alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
- Andere Bezeichnung
- TOP2A / Topoisomerase II alpha (TOP2A Produkte)
- Hintergrund
- This mAb recognizes an ~170 kDa protein which is identified as Topoisomerase IIa, and shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells.
- Gen-ID
- 7153
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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