NADPH Oxidase 4 Antikörper

Produktnummer ABIN4949834

Der Maus Monoklonal anti-NADPH Oxidase 4 Antikörper (Klon NOX4-1245) (ABIN4949834) detektiert spezifisch NADPH Oxidase 4 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NADPH Oxidase 4 Antikörper (ABIN4949834)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Klon: NOX4-1245

Produktdetails anti-NADPH Oxidase 4 Antikörper

Verwendungszweck: NOX4 Antibody / NADPH Oxidase 4 (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: Human recombinant protein was used as the immunogen for this NOX4 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Titering of the NOX4 antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the NOX4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration