Rekombinanter PD-1 Antikörper

Produktnummer ABIN4949389

Der Kaninchen Monoklonal Anti-PD-1-Antikörper wurde für FACS, IF und IHC (p) validiert. Er ist geeignet, PD-1 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter PD-1 Antikörper (ABIN4949389)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PDCD1-1410R

Produktdetails anti-PD-1 Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant PD1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1),Immunofluorescence: 1-2 μg/mL,FACS: 0.5-1 μg/10e6 cells in 0.1ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PDCD1 / PD-1

Hintergrund: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

Pathways: Cancer Immune Checkpoints