PD-1 Antikörper

Produktnummer ABIN4949386

Der Kaninchen Polyklonal Anti-PD-1-Antikörper wurde für FACS, IF und IHC (p) validiert. Er ist geeignet, PD-1 in Proben von Human zu detektieren.

Kurzübersicht für PD-1 Antikörper (ABIN4949386)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PD-1 Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: A full-length human protein was used as the immunogen for the PD1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titering of the PD1 antibody may be required for optimal performance.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Immunofluorescence: 1-2 μg/mL,FACS: 0.5-1 μg/10e6 cells in 0.1ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PDCD1 / PD-1

Hintergrund: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

Pathways: Cancer Immune Checkpoints