APEX1 Antikörper
Kurzübersicht für APEX1 Antikörper (ABIN4906178)
Target
Alle APEX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Purified by Protein G.
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Immunogen
- This APEX1 antibody is generated from a mouse immunized with a recombinant protein of human APEX1.
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Isotyp
- IgG1
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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Andere Bezeichnung
- APEX1
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Hintergrund
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Synonyms: APE, APX, APE1, APEN, APEX, HAP1, REF1, DNA-(apurinic or apyrimidinic site) lyase, APEX nuclease, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1, APEX1
Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein. [provided by RefSeq, Jul 2008]
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Gen-ID
- 328
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UniProt
- P27695
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Pathways
- DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
Target
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