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CD3 Antikörper

CD3 Reaktivität: Human FACS, IHC, IHC (fro), Func Wirt: Maus Monoclonal OKT3 unconjugated

Produktnummer ABIN490182

Datenblatt (PDF)

Target Alle CD3 Antikörper anzeigen

CD3
Reaktivität
214

109

35

20

17

10

8

8

7

7

7

3

3

2

2
Human
Wirt
258

60

20

13

9

2
Maus
Passende Sekundärantikörper
Klonalität
350

6

1
Monoklonal
Konjugat
104

42

33

26

25

13

10

9

8

8

8

6

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD3 Antikörper ist unkonjugiert
Applikation
313

93

62

60

47

44

40

24

17

10

9

8

7

7

6

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Spezifität

The mouse monoclonal antibody OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia. HLDA VI, WS Code T6T-R3.

Aufreinigung

Protein G purified

Endotoxin-Niveau

Low Endotoxin

Immunogen

Type of Immunogen: Native protein

Klon

OKT3

Isotyp

IgG2a

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anti-CD3 (CD3) antibody (Biotin)
CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal UCHT1 Biotin

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anti-CD3 (CD3) antibody (PerCP)
CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 PerCP

anti-CD3 (CD3) antibody (APC)
CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 APC

Applikationshinweise

Approved: Flo, Func, IHC, IHC-Fr

Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Functional Application: counteracting both generation and function of effector T cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Kommentare

Target Species of Antibody: Human

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Azide-free PBS,  pH 7.4, 0.2 micron filter sterilized

Konservierungsmittel

Azide free

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

avoid freeze thaw cycles.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Target

CD3

Andere Bezeichnung

CD3 (CD3 Produkte)

Pathways

T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway