CD3 Antikörper
Kurzübersicht für CD3 Antikörper (ABIN490172)
Target
Alle CD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The mouse monoclonal antibody OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia. HLDA VI, WS Code T6T-R3.
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Aufreinigung
- Protein G purified
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Immunogen
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Type of Immunogen: Native protein -
Isotyp
- IgG2a
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Applikationshinweise
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Approved: Flo, Func, IHC, IHC-Fr, Inhb
Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Functional Application: counteracting both generation and function of effector T cells. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- avoid freeze thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- CD3
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Andere Bezeichnung
- CD3
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Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
Target
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