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CD46 Antikörper

CD46 Reaktivität: Human WB, FACS, ELISA, IHC (p) Wirt: Maus Monoclonal 3F1 unconjugated

Produktnummer ABIN4889041

Datenblatt (PDF)

Target Alle CD46 Antikörper anzeigen

CD46
Reaktivität
123

34

20

10

10

3
Human
Wirt
80

60

2

1
Maus
Passende Sekundärantikörper
Klonalität
73

70
Monoklonal
Konjugat
56

14

14

10

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD46 Antikörper ist unkonjugiert
Applikation
84

82

38

37

28

17

14

14

13

9

7

5

5

2

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

Reacts with human 44 kDa CD46 protein

Kreuzreaktivität (Details)

Diffuse and duplicated bands can be seen due to the glycosylation of CD46.

Aufreinigung

Purified (protein A)

Immunogen

Recombinant CD46 protein

Klon

3F1

Isotyp

IgG1 kappa

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CD46 Reaktivität: Human, Maus WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

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CD46 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21743 unconjugated

anti-CD46 (CD46) antibody (Biotin)
CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 Biotin

anti-CD46 (CD46) antibody (FITC)
CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 FITC

Applikationshinweise

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA1:20 000 - 1:100 000 IHC-P10 μg/mL WB1:2000 - 1:10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Must be reconstituted in distilled water.

Konzentration

1 mg/mL

Buffer

PBS

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit

24 months
Target

CD46

Andere Bezeichnung

CD46 / Membrane Cofactor Protein (CD46 Produkte)

Hintergrund

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Gen-ID

4179

UniProt

P15529

Pathways

Regulation of Actin Filament Polymerization