XIAP Antikörper (AA 15-244)

Produktnummer ABIN4886770

Produktdetails anti-XIAP Antikörper

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Bindungsspezifität: AA 15-244

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XIAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: X-linked inhibitor of apoptosis
Protein Name: E3 ubiquitin-protein ligase XIAP

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human XIAP recombinant protein (Position: A15-V244). Human XIAP shares 89.4% and 90.7% amino acid (aa) sequence identity with mouse and rat XIAP, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-XIAP Antikörper (ABIN4886770)

Chen, Mao, Qiu, Liu: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." in: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).

Details zu XIAP

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Andere Bezeichnung: XIAP (XIAP Produkte)

Synonyme: API3 antikoerper, BIRC4 antikoerper, IAP-3 antikoerper, ILP1 antikoerper, MIHA antikoerper, XLP2 antikoerper, hIAP-3 antikoerper, hIAP3 antikoerper, api3 antikoerper, birc4 antikoerper, ilp1 antikoerper, miha antikoerper, xlp2 antikoerper, xxiap antikoerper, 1110015C02Rik antikoerper, Aipa antikoerper, Api3 antikoerper, Birc4 antikoerper, IAP3 antikoerper, ILP-1 antikoerper, mXIAP antikoerper, riap3 antikoerper, fb73d01 antikoerper, wu:fb73d01 antikoerper, zgc:91873 antikoerper, BIRC8 antikoerper, X-linked inhibitor of apoptosis antikoerper, X-linked inhibitor of apoptosis L homeolog antikoerper, XIAP antikoerper, xiap antikoerper, xiap.L antikoerper, Xiap antikoerper

Hintergrund: XIAP, also known as IAP3 or BIRC4, is a protein that stops apoptotic cell death. It is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants.

Synonyms: API3 | Api3 | Birc4 | API 3 | BIRC4 | IAP3 | BIRC 4 | E3 ubiquitin-protein ligase XIAP | hIAP3 | hIAP-3 | HILP | IAP 3 | IAP-like protein | ILP 1 | X linked IAP | X-linked IAP | X-linked inhibitor of apoptosis | XLP2 | P98170

Gen-ID: 331

UniProt: P98170

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Transition Metal Ion Homeostasis