APC2 Antikörper (N-Term)

Produktnummer ABIN4886464

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch APC2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APC2 Antikörper (N-Term) (ABIN4886464)

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-APC2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-APC2 Antibody

Sequenz: KHLQGKLEQE ARVLVSSGQT EVLEQLKALQ MDITSLYNLK

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by two amino acids.

Produktmerkmale: Anti-APC2 Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human APC2, different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu APC2

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Andere Bezeichnung: APC2

Hintergrund:

Background: APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

Gene Full Name: APC regulator of Wnt signaling pathway 2

Molekulargewicht: 94 kDa

Gen-ID: 10297

UniProt: O95996

Pathways: WNT Signalweg