ACO2 Antikörper (C-Term)

Produktnummer ABIN4886417

Der Kaninchen Polyklonal Anti-ACO2-Antikörper wurde für WB validiert. Er ist geeignet, ACO2 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für ACO2 Antikörper (C-Term) (ABIN4886417)

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACO2 Antikörper

Bindungsspezifität: AA 561-596, C-Term

Verwendungszweck: Anti-Aconitase 2/ACO2 Antibody Picoband®

Sequenz: TSQRLQLLEP FDKWDGKDLE DLQILIKVKG KCTTDH

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Aconitase 2/ACO2 Antibody Picoband® (ABIN4886417). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aconitase 2, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: Aconitase 2, mitochondrial". 2. Geurts van Kessel, A. H. M., Westerveld, A., de Groot, P. G., Meera Khan, P., Hagemeijer, A. Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. Cytogenet. Cell Genet. 28: 169-172, 1980. 3. Mirel, D. B., Marder, K., Graziano, J., Freyer, G., Zhao, Q., Mayeux, R., Wilhelmsen, K. C. Characterization of the human mitochondrial aconitase gene (ACO2). Gene 213: 205-218, 1998.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu ACO2

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Andere Bezeichnung: ACO2

Hintergrund:

Synonyms: Aconitate hydratase, mitochondrial,Aconitase,4.2.1.3,Citrate hydro-lyase,ACO2,

Tissue Specificity: Highly enriched in the brain. Much weaker expression in heart, lung and muscle.

Background: Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

Molekulargewicht: 85 kDa

Gen-ID: 50

UniProt: Q99798