Integrin Alpha2b Antikörper
Kurzübersicht für Integrin Alpha2b Antikörper (ABIN4880137)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- CD41 Monoclonal Antibody [M148]
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Spezifität
- This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.
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Aufreinigung
- Purified on protein A from tissue culture supernatant.
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Immunogen
- Homogenized human medulloblastoma tissue.
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Isotyp
- IgG1
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p), Func Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal antibody dilution should be determined by titration
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Kommentare
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Myeloma/fusion partners:Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Integrin Alpha2b (CD41)
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Andere Bezeichnung
- CD41
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Hintergrund
- CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, integrin alpha 2b, Integrin alpha-IIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), ITA2B, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, Platelet membrane glycoprotein IIb, platelet-specific antigen BAK
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Gen-ID
- 3689
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OMIM
- 607759
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UniProt
- P08514
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Pathways
- Integrin Complex
Target
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