Integrin Alpha2b Antikörper
Kurzübersicht für Integrin Alpha2b Antikörper (ABIN4880137)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.
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Aufreinigung
- Purified on protein A from tissue culture supernatant.
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Immunogen
- Homogenized human medulloblastoma tissue.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal antibody dilution should be determined by titration
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Kommentare
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Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Integrin Alpha2b (CD41)
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Andere Bezeichnung
- CD41
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Gen-ID
- 3689
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OMIM
- 607759
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UniProt
- P20701
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Pathways
- Integrin Complex
Target
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