ATM Antikörper (AA 992-1144) (FITC)
Kurzübersicht für ATM Antikörper (AA 992-1144) (FITC) (ABIN4880063)
Target
Alle ATM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 992-1144
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Spezifität
- This antibody recognises ataxia telangiectasia mutated (ATM), a 370 kDa serine protein kinase. The ATM protein is a member of the phosphatidylinositol-3 kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control.
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Aufreinigung
- Purified on protein A from tissue culture supernatant.
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Immunogen
- Fusion protein corresponding to amino acid residues 992-1144 of ATM
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Isotyp
- IgG1
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Applikationshinweise
- Optimal antibody dilution should be determined by titration
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Kommentare
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Myeloma, fusion partnersCells from immunized mice were fused with the Sp2/0-Ag.14 myeloma cell line
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Purified IgG conjugated to Fluoroscein using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- ATM (Ataxia Telangiectasia Mutated (ATM))
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Andere Bezeichnung
- ATM
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Gen-ID
- 472
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OMIM
- 607585
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Pathways
- p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Target
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