CD44 Antikörper

Produktnummer ABIN487498

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD44 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD44 Antikörper (ABIN487498)

Target: CD44

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 156-3C11

Produktdetails anti-CD44 Antikörper

Spezifität: This antibody is specific to a cell surface glycoprotein of 80-95 kDa, known as CD44, which is expressed on the surface of lymphocytes, monocytes, and granulocytes. This antibody reacts with red cells pretreated with 2-aminoethyl-isothiouronium bromide (AET).
Cellular Localization: Cell membrane.

Produktmerkmale: Synonyms: CDw44, PGP-I, ECMR-III, Hermes antigen, Epican, LHR, MDU2, MDU3, MIC4, Phagocyticglycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesionreceptor, Hyaluronate receptor, Heparan sulfate proteoglycan

Aufreinigung: Purified

Immunogen: BALB/C mice were injected with stimulated Human leukocytes.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry and Paraffin Sections: Use at 1/25-1/75 in ABC method. Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Human tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

Gen-ID: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling