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EGFR Antikörper (Internal Region)

Dieses Schaf Polyklonal-Antikörper erkennt spezifisch EGFR in WB, ELISA, IHC, IF, IHC (p), IP und ICC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Huhn.
Produktnummer ABIN457474

Kurzübersicht für EGFR Antikörper (Internal Region) (ABIN457474)

Target

Alle EGFR Antikörper anzeigen
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität

  • 817
  • 297
  • 286
  • 25
  • 25
  • 23
  • 20
  • 14
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Huhn

Wirt

  • 592
  • 225
  • 14
  • 13
  • 4
  • 3
  • 1
  • 1
  • 1
Schaf

Klonalität

  • 534
  • 315
  • 2
Polyklonal

Konjugat

  • 433
  • 64
  • 28
  • 21
  • 18
  • 18
  • 18
  • 17
  • 16
  • 16
  • 16
  • 13
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
Dieser EGFR Antikörper ist unkonjugiert

Applikation

  • 581
  • 252
  • 183
  • 160
  • 140
  • 108
  • 102
  • 92
  • 82
  • 63
  • 37
  • 34
  • 33
  • 22
  • 19
  • 11
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 41
    • 40
    • 31
    • 31
    • 29
    • 28
    • 27
    • 27
    • 26
    • 22
    • 22
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 13
    • 12
    • 12
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Internal Region

    Marke

    IHC-plus™

    Spezifität

    Recognizes human Epidermal Growth Factor Receptor.

    Aufreinigung

    Protein G purified

    Immunogen

    Recombinant 20aa residues representing a portion of the internal domain of EGFR proximal to the phosphorylation region.

    Type of Immunogen: Recombinant protein

    Isotyp

    IgG
  • Applikationshinweise

    Approved: ELISA, ICC, IF, IHC, IHC-P (5 μg/mL), IP, WB

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

    Kommentare

    Target Species of Antibody: Human

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    0.15 M PBS,  pH 7.4. No preservatives added.

    Konservierungsmittel

    Without preservative

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Andere Bezeichnung

    EGFR

    Hintergrund

    Name/Gene ID: EGFR
    Subfamily: EGF Receptor
    Family: Protein Kinase

    Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1

    Gen-ID

    1956

    UniProt

    P00533

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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