-
- Target Alle CD22 Antikörper anzeigen
- CD22 (CD22 Molecule (CD22))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD22 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS)
- Spezifität
- The antibody IS7 reacts with an extracellular epitope of CD22 (BL-CAM), a 130 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed in the cytoplasm of pro-B and pre-B lymphocytes, and on the surface of mature and activated B lymphocytes, it is lost on plasma cells, peripheral blood T lymphocytes, granulocytes and monocytes.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- human cell line Reh
- Klon
- IS7
- Isotyp
- IgG1
- Top Product
- Discover our top product CD22 Primärantikörper
-
anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reaktivität: Human FACS, WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 2H1C4 unconjugated
anti-CD22 Molecule (CD22) (AA 621-725) antibodyCD22 Reaktivität: Human FACS, ELISA, ICC Wirt: Maus Monoclonal 1A3A11 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reaktivität: Human FACS, WB, ELISA, IHC, IF, Coat, StM Wirt: Maus Monoclonal BLCAM-1795 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reaktivität: Human FACS, WB, ELISA, IHC, IF, Coat Wirt: Maus Monoclonal BLCAM-1796 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reaktivität: Human, Non-Human Primate FACS, WB, IP Wirt: Maus Monoclonal MEM-01 unconjugated
anti-CD22 Molecule (CD22) antibody (PE)CD22 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-01 PE
anti-CD22 Molecule (CD22) antibody (FITC)CD22 Reaktivität: Human FACS Wirt: Maus Monoclonal IS7 FITC
anti-CD22 Molecule (CD22) (AA 708-847) antibodyCD22 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reaktivität: Human, Maus, Ratte, Affe, Hund WB, IHC, IHC (p) Wirt: Maus Monoclonal 4C3 unconjugated
anti-CD22 Molecule (CD22) (AA 20-687) antibodyCD22 Reaktivität: Human FACS, WB, ELISA, IF, IP Wirt: Kaninchen Monoclonal DM13 unconjugated
-
- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL, Positive control: lysed whole blood, lyse-wash protocol
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Konservierungsmittel
- Azide free
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
-
- Target
- CD22 (CD22 Molecule (CD22))
- Andere Bezeichnung
- CD22 (CD22 Produkte)
- Hintergrund
- CD22 Molecule,CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.,SIGLEC2, SIGLEC-2
- Gen-ID
- 933
- UniProt
- P20273
-
Sie sind hier:
