TLR3 Antikörper
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- Target Alle TLR3 Antikörper anzeigen
- TLR3 (Toll-Like Receptor 3 (TLR3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TLR3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to TLR3.
- Aufreinigung
- Affinity chromatography on Protein A
- Immunogen
- Recombinant TLR3 protein
- Top Product
- Discover our top product TLR3 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Andere Bezeichnung
- CD283 / TLR3 (TLR3 Produkte)
- Synonyme
- CD283 antikoerper, IIAE2 antikoerper, AI957183 antikoerper, zgc:123006 antikoerper, toll like receptor 3 antikoerper, toll-like receptor 3 antikoerper, TLR3 antikoerper, Tlr3 antikoerper, tlr3 antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.Synonyms: Toll-like receptor 3
- Gen-ID
- 7098
- NCBI Accession
- NP_003256
- UniProt
- O15455
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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