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PSMA7 Antikörper (Middle Region)

Dieses Anti-PSMA7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PSMA7 in WB und EIA. Geeignet für Human und Maus.
Produktnummer ABIN453792

Kurzübersicht für PSMA7 Antikörper (Middle Region) (ABIN453792)

Target

Alle PSMA7 Antikörper anzeigen
PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Reaktivität

  • 55
  • 26
  • 18
  • 1
Human, Maus

Wirt

  • 46
  • 9
Kaninchen

Klonalität

  • 47
  • 8
Polyklonal

Konjugat

  • 27
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PSMA7 Antikörper ist unkonjugiert

Applikation

  • 46
  • 21
  • 16
  • 13
  • 8
  • 8
  • 8
  • 4
  • 4
  • 2
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Spezifität

    This antibody reacts to PSMA7.

    Aufreinigung

    Affinity chromatography on Protein A

    Immunogen

    KLH conjugated synthetic peptide selected from the Center region of human PSMA7
  • Applikationshinweise

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

    Andere Bezeichnung

    PSMA7

    Hintergrund

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA7 is a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension.Synonyms: HSPC, Proteasome subunit RC6-1, Proteasome subunit XAPC7, Proteasome subunit alpha type-7

    Gen-ID

    5688

    NCBI Accession

    NP_002783

    UniProt

    O14818

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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