CTPS2 Antikörper (N-Term)

Produktnummer ABIN453590

Der Kaninchen Polyklonal Anti-CTPS2-Antikörper wurde für WB und EIA validiert. Er ist geeignet, CTPS2 in Proben von Human zu detektieren.

Kurzübersicht für CTPS2 Antikörper (N-Term) (ABIN453590)

Target: CTPS2 (CTP Synthase II (CTPS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CTPS2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to CTPS2.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the N-term region of human CTPS2

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Andere Bezeichnung: CTP Synthase 2

Hintergrund: CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.Synonyms: CTP synthetase 2, CTPS2, UTP-ammonia ligase 2

Gen-ID: 56474

NCBI Accession: NP_001137474

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process