BMI1 Antikörper
Kurzübersicht für BMI1 Antikörper (ABIN453535)
Target
Alle BMI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody reacts to BMI-1 / RNF51.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- BMI1 recombinant protein
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Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Andere Bezeichnung
- BMI-1 / RNF51
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Hintergrund
- Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.Synonyms: BMI1, PCGF4, Polycomb group RING finger protein 4, RING finger protein 51
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Gen-ID
- 648
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NCBI Accession
- NP_005171
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UniProt
- P35226
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Pathways
- Zellzyklus, Autophagie
Target
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