Prostate Specific Antigen Antikörper (free)

Produktnummer ABIN452575

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Prostate Specific Antigen in EIA und ELISA (Capture). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Prostate Specific Antigen Antikörper (free) (ABIN452575)

Target: Prostate Specific Antigen (PSA)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Capture)

Klon: 108

Produktdetails anti-Prostate Specific Antigen Antikörper

Bindungsspezifität: free

Spezifität: This monoclonal antibody reacts with Human free PSA, but does not react with complexed PSA.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Purified Human Free PSA.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: This monoclonal PSA antibody can be used as Capture antibody in a SandwichELISA for Human free PSA detection in combination with a HRP-conjugated Tracer antibody. Suggested Capture Coating Dose: 0.5 μg/well. Substrate: TMB. If the above suggestedconditions are followed approximately 22 pg/mL of Free PSA can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distilled water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: Kallikrein-3 / PSA / KLK3

Hintergrund: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase

Gen-ID: 354

UniProt: P07288

Pathways: Komplementsystem