Metabotropic Glutamate Receptor 6 Antikörper (C-Term)

Produktnummer ABIN437971

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Metabotropic Glutamate Receptor 6 in WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Ratte und Maus.

Kurzübersicht für Metabotropic Glutamate Receptor 6 Antikörper (C-Term) (ABIN437971)

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Produktdetails anti-Metabotropic Glutamate Receptor 6 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: affinity purified

Immunogen: AAPPQNENAEDAK
Corresponding to the carboxyterminus of rat mGluR6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blot: 1:2000-1:3000
Immunohistochemistry: 1:300
Dilutions listed as a recommendation. Optimal dilution should be determined by investigator

Kommentare:

This antibody is useful for Western blot, where a band is seen at approx. 96 kDa. Neurons of expected brain regions stain well. Staining is not recommended for human or rat tissues
Note: A customer found a band in the 60-70 kDa range corresponding to the mGluR6 precursor.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1 % BSA, Tris-glycine with 0.1 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Aliquot as undiluted antisera and immediately place at -20°C.
Antisera may have become trapped in top of vial during shipping. Centrifugation of vial is recommended before opening.
Repeated freeze/thaw cycles compromise the integrity of the antiserum.

Lagerung: -20 °C

Haltbarkeit: 6 months

Details zu Metabotropic Glutamate Receptor 6

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Andere Bezeichnung: mGluR6

Hintergrund: Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.