Metabotropic Glutamate Receptor 6 Antikörper (AA 480-585)

Produktnummer ABIN5611180

Produktdetails anti-Metabotropic Glutamate Receptor 6 Antikörper

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Bindungsspezifität: AA 480-585

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human GRM6 (AA: extra 480-585) expressed in E. coli.

Klon: 7D9C9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu Metabotropic Glutamate Receptor 6

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Andere Bezeichnung: GRM6 (GRM6 Produkte)

Synonyme: mGluR6 antikoerper, CSNB1B antikoerper, GPRC1F antikoerper, MGLUR6 antikoerper, mGlu6 antikoerper, GRM6 antikoerper, BC021919 antikoerper, Gm3 antikoerper, Gprc1f antikoerper, nerg1 antikoerper, nob2 antikoerper, nob3 antikoerper, nob4 antikoerper, si:dkey-52h10.3 antikoerper, cb496 antikoerper, grma antikoerper, zK13A21.16 antikoerper, zgc:158329 antikoerper, glutamate metabotropic receptor 6 antikoerper, glutamate receptor, metabotropic 6 antikoerper, glutamate receptor, metabotropic 6a antikoerper, glutamate receptor, metabotropic 6b antikoerper, Grm6 antikoerper, GRM6 antikoerper, grm6a antikoerper, grm6b antikoerper

Hintergrund:

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Aliases: mGlu6, CSNB1B, GPRC1F, MGLUR6

Molekulargewicht: 95.5 kDa

Gen-ID: 2916

HGNC: 2916