Metabotropic Glutamate Receptor 6 Antikörper (C-Term)
Kurzübersicht für Metabotropic Glutamate Receptor 6 Antikörper (C-Term) (ABIN2779742)
Target
Alle Metabotropic Glutamate Receptor 6 (GRM6) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- GRM6 Antibody - C-terminal region
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Sequenz
- ITFSLTSLQV VGMIAWLGAR PPHSVIDYEE QRTVDPEQAR GVLKCDMSDL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GRM6. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human GRM6
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101616
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
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Andere Bezeichnung
- GRM6
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Hintergrund
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Background Information: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade.
Gene Name: Glutamate receptor, metabotropic 6
Alternative Symbols: mGlu6, CSNB1B, GPRC1F, MGLUR6
Protein Name: Metabotropic glutamate receptor 6
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Molekulargewicht
- 95kDa
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Gen-ID
- 2916
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NCBI Accession
- NP_000834
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UniProt
- O15303
Target
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