Mre11 Antikörper (AA 578-590)
Kurzübersicht für Mre11 Antikörper (AA 578-590) (ABIN401304)
Target
Alle Mre11 (MRE11A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 578-590
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Spezifität
- This antibody is directed against Saccharomyces cerevisiae Mre11 protein.
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Aufreinigung
- Affinity Purified
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Immunogen
- Synthetic peptide corresponding to amino acids 578-590 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein
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Isotyp
- IgG
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Applikationshinweise
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ELISA: 1/10000 - 1/50000. Western Blot: 1/200 - 1/2000. ChIP.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.19 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH containing 0.01 % (w/v) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Andere Bezeichnung
- MRE11
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Hintergrund
- Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability. Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function. This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.Synonyms: Double-strand break repair protein MRE11A, HNGS1, MRE11 homolog 1, MRE11 meiotic recombination 11 homolog A, MRE11A
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Gen-ID
- 855264
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NCBI Accession
- NP_013951
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UniProt
- P32829
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Pathways
- DNA Reparatur
Target
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