PDPK1 Antikörper (AA 29-436)

Produktnummer ABIN400866

Dieses Anti-PDPK1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PDPK1 in WB und EIA. Geeignet für Human und Ratte.

Kurzübersicht für PDPK1 Antikörper (AA 29-436) (ABIN400866)

Target: PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDPK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT2D6

Produktdetails anti-PDPK1 Antikörper

Bindungsspezifität: AA 29-436

Spezifität: The antibody recognizes human and rat PDK1. Other species not tested.

Produktmerkmale: Synonyms: Pyruvate dehydrogenase kinase isoform 1, Pyruvate dehydrogenase [lipoamide] kinaseisozyme 1 mitochondrial

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human PDK1 (29-436 aa) purified from E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (1: 250 - 1: 1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PDPK1

Target: PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Andere Bezeichnung: PDK1

Hintergrund: PDK1 (pyruvate dehydrogenase kinase isoform 1) is involved in the regulation of enzymatic activity of mammalian pyruvate dehydrogenase (PDH) that is a part of a mitochondrial multienzyme complex to catalyze the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. PDK1 has been found to serve as an effective therapeutic target for inhibition of glioblastoma growth.Synonyms: Pyruvate dehydrogenase [lipoamide] kinase isozyme 1 mitochondrial, Pyruvate dehydrogenase kinase isoform 1

Gen-ID: 5163

UniProt: Q15118

Pathways: PI3K-Akt Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals