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CD22 Antikörper

CD22 Reaktivität: Human FACS Wirt: Maus Monoclonal IS7 unconjugated

Produktnummer ABIN400636

Datenblatt (PDF)

Target Alle CD22 Antikörper anzeigen

CD22 (CD22 Molecule (CD22))
Reaktivität
143

58

23

5

3

2

2

1
Human
Wirt
93

66

17

1
Maus
Passende Sekundärantikörper
Klonalität
118

57

1
Monoklonal
Konjugat
92

14

13

9

7

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD22 Antikörper ist unkonjugiert
Applikation
106

77

49

38

35

21

13

12

11

8

5

4

3

3

3

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Produktmerkmale

Synonyms: SIGLEC2, Siglec-2, B-cell receptor CD22, Leu-14, BL-CAM, Sialic acid-binding Ig-like lectin 2,B-lymphocyte cell adhesion molecule

Aufreinigung

Protein A affinity chromatography

Reinheit

> 95 % by SDS-PAGE

Immunogen

Reh human cell line

Klon

IS7

Isotyp

IgG1

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anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reaktivität: Human FACS, WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 2H1C4 unconjugated

anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reaktivität: Human FACS, ELISA, ICC Wirt: Maus Monoclonal 1A3A11 unconjugated

anti-CD22 Molecule (CD22) (AA 52-178) antibody
CD22 Reaktivität: Human FACS, WB, ELISA, IHC, IF, Coat, StM Wirt: Maus Monoclonal BLCAM-1795 unconjugated

anti-CD22 Molecule (CD22) (AA 52-178) antibody
CD22 Reaktivität: Human FACS, WB, ELISA, IHC, IF, Coat Wirt: Maus Monoclonal BLCAM-1796 unconjugated

anti-CD22 Molecule (CD22) antibody
CD22 Reaktivität: Human, Non-Human Primate FACS, WB, IP Wirt: Maus Monoclonal MEM-01 unconjugated

anti-CD22 Molecule (CD22) antibody (PE)
CD22 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-01 PE

anti-CD22 Molecule (CD22) antibody (FITC)
CD22 Reaktivität: Human FACS Wirt: Maus Monoclonal IS7 FITC

anti-CD22 Molecule (CD22) (AA 708-847) antibody
CD22 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD22 Molecule (CD22) antibody
CD22 Reaktivität: Human, Maus, Ratte, Affe, Hund WB, IHC, IHC (p) Wirt: Maus Monoclonal 4C3 unconjugated

anti-CD22 Molecule (CD22) (AA 20-687) antibody
CD22 Reaktivität: Human FACS, WB, ELISA, IF, IP Wirt: Kaninchen Monoclonal DM13 unconjugated

Applikationshinweise

Flow Cytometry. Positive control: lysed whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized.

Konservierungsmittel

Azide free

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch.

Haltbarkeit

12 months
Target

CD22 (CD22 Molecule (CD22))

Andere Bezeichnung

CD22 (CD22 Produkte)

Hintergrund

CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.Synonyms: B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14, SIGLEC2, Sialic acid-binding Ig-like lectin 2, Siglec-2

UniProt

P20273