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IRAK3 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRAK3 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN392236

Kurzübersicht für IRAK3 Antikörper (N-Term) (ABIN392236)

Target

Alle IRAK3 Antikörper anzeigen
IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reaktivität

  • 51
  • 30
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 66
  • 8
  • 1
Kaninchen

Klonalität

  • 59
  • 16
Polyklonal

Konjugat

  • 42
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IRAK3 Antikörper ist unkonjugiert

Applikation

  • 66
  • 31
  • 13
  • 13
  • 13
  • 8
  • 8
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB2344
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 45-77, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This IRAK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-77 amino acids from the N-terminal region of human IRAK3.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:500. IHC-P: 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

    Andere Bezeichnung

    IRAK3

    Hintergrund

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

    Molekulargewicht

    67767

    Gen-ID

    11213

    NCBI Accession

    NP_001135995, NP_009130

    UniProt

    Q9Y616

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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