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VEGFR2/CD309 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-VEGFR2/CD309-Antikörper wurde für WB, FACS, IF und IHC (p) validiert. Er ist geeignet, VEGFR2/CD309 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN391979

Kurzübersicht für VEGFR2/CD309 Antikörper (C-Term) (ABIN391979)

Target

Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reaktivität

  • 329
  • 212
  • 145
  • 17
  • 11
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 299
  • 73
  • 35
  • 4
  • 1
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 290
  • 125
Polyklonal

Konjugat

  • 187
  • 36
  • 21
  • 14
  • 11
  • 9
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert

Applikation

  • 233
  • 131
  • 120
  • 117
  • 65
  • 42
  • 42
  • 26
  • 25
  • 16
  • 13
  • 13
  • 9
  • 7
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB01536
  • Bindungsspezifität

    • 37
    • 34
    • 27
    • 23
    • 20
    • 16
    • 16
    • 13
    • 13
    • 11
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1326-1356, C-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This VEGFR2 (FLK1/KDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1326-1356 amino acids from the C-terminal region of human VEGFR2 (FLK1/KDR).

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Kovács, Decatur, Toro, Pham, Liu, Jing, Murray, Lampidis, Merchan: "2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation." in: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 264-75, (2016) (PubMed).

  • Target

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    Andere Bezeichnung

    VEGFR2 (FLK1/KDR)

    Hintergrund

    KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

    Molekulargewicht

    151527

    Gen-ID

    3791

    NCBI Accession

    NP_002244

    UniProt

    P35968

    Pathways

    RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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