Der Kaninchen Polyklonal Anti-VEGFR2/CD309-Antikörper wurde für WB, FACS, IF und IHC (p) validiert. Er ist geeignet, VEGFR2/CD309 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This VEGFR2 (FLK1/KDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1326-1356 amino acids from the C-terminal region of human VEGFR2 (FLK1/KDR).
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Kovács, Decatur, Toro, Pham, Liu, Jing, Murray, Lampidis, Merchan: "2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation." in: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 264-75, (2016) (PubMed).
Target
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Andere Bezeichnung
VEGFR2 (FLK1/KDR)
Hintergrund
KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.