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VEGFR2/CD309 Antikörper (C-Term)

Name: VEGFR2/CD309 Antikörper (C-Term)
SKU: ABIN391979
Price: 467.5 EUR
Availability: InStock

VEGFR2 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB01536 unconjugated

Western blot analysis of anti-KDR/FLK1 Pab (ABIN391979 and ABIN2841770) in HeLa cell lysate. (VEGFR2/CD309 Antikörper (C-Term))

VEGFR2 (FLK1/KDR) Antibody (C-term) (ABIN391979 and ABIN2841770) flow cytometric analysis of MDA-M cells (right histogram) compared to a negative control cell (left histogram). (VEGFR2/CD309 Antikörper (C-Term))

FACS

Confocal immunofluorescent analysis of VEGFR2 (FLK1/KDR) Antibody (C-term) (ABIN391979 and ABIN2841770) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (VEGFR2/CD309 Antikörper (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (VEGFR2/CD309 Antikörper (C-Term))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN391979

Datenblatt (PDF)

Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Bindungsspezifität
37

34

27

23

20

16

16

11

10

10

8

7

5

5

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1326-1356, C-Term
Reaktivität
311

200

144

17

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
Human
Wirt
289

60

24

3

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
281

97
Polyklonal
Konjugat
168

31

19

14

10

9

9

8

7

7

7

7

6

6

6

6

6

6

6

6

6

6

6

3

2

2

2

1

1

1

1

1

1

1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
Applikation
213

122

100

98

63

27

26

24

18

14

13

9

7

7

7

6

3

2

2

2

2

2

2

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This VEGFR2 (FLK1/KDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1326-1356 amino acids from the C-terminal region of human VEGFR2 (FLK1/KDR).

Klon

RB01536

Isotyp

Ig Fraction

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Applikationshinweise

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Kovács, Decatur, Toro, Pham, Liu, Jing, Murray, Lampidis, Merchan: "2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation." in: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 264-75, (2016) (PubMed).
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung

VEGFR2 (FLK1/KDR) (VEGFR2 Produkte)

Hintergrund

KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

Molekulargewicht

151527

Gen-ID

3791

NCBI Accession

NP_002244

UniProt

P35968

Pathways

RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling