Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

LKB1 Antikörper (N-Term)

Name: LKB1 Antikörper (N-Term)
SKU: ABIN391350
Price: 445.5 EUR
Availability: InStock

STK11 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB3547 unconjugated

Western blot analysis of STK11 (arrow) using rabbit polyclonal STK11 Antibody (ABIN391350 and ABIN2841371).

STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control cell (left histogram).

FACS

Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

STK11 Antibody (I29) (ABIN391350 and ABIN2841371) western blot analysis in T47D cell line lysates (35 μg/lane).

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

5 Abbildungen

(1 reference)

Produktnummer ABIN391350

Datenblatt (PDF)

Target Alle LKB1 (STK11) Antikörper anzeigen

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
Bindungsspezifität
27

23

20

19

15

15

8

7

7

7

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 14-44, N-Term
Reaktivität
172

115

63

16

15

7

6

5

4

3

3

3

2

1

1
Human
Wirt
177

9
Kaninchen
Passende Sekundärantikörper
Klonalität
180

6
Polyklonal
Konjugat
80

11

9

9

7

7

7

7

7

7

5

5

5

5

5

4

4

2
Dieser LKB1 Antikörper ist unkonjugiert
Applikation
140

74

65

65

33

27

20

15

6

4

3

2

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

C, M, Rat, X

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).

Klon

RB3547

Isotyp

Ig Fraction

Top Product

Discover our top product STK11 Primärantikörper
anti-serine/threonine Kinase 11 (STK11) (AA 134-433) antibody
STK11 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) antibody
STK11 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 14-44) antibody
STK11 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 393-420), (C-Term) antibody
STK11 Reaktivität: Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB37144 unconjugated

anti-serine/threonine Kinase 11 (STK11) (pSer428) antibody
STK11 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 19-48) antibody
STK11 Reaktivität: Human WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Tyr1313) antibody
STK11 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) antibody
STK11 Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 4H12 unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 1-433) antibody
STK11 Reaktivität: Human WB, IF, PLA Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Internal Region) antibody
STK11 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Haltbarkeit

6 months
Sohn, Jang, Campan, Weisenberger, Dickhout, Wang, Cho, Yates, Lucock, Chiang, Austin, Choi, Laird, Kim et al.: "The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer ..." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 1999-2005, (2009) (PubMed).
Target

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Andere Bezeichnung

STK11 (LKB1) (STK11 Produkte)

Synonyme

pjs antikoerper, LKB1 antikoerper, XEEK1 antikoerper, Stk11 antikoerper, PJS antikoerper, hLKB1 antikoerper, AA408040 antikoerper, Lkb1 antikoerper, Par-4 antikoerper, R75140 antikoerper, mLKB1 antikoerper, wu:fj61a05 antikoerper, zgc:110180 antikoerper, xeek1 antikoerper, serine/threonine kinase 11 antikoerper, polarization-related protein LKB1 antikoerper, serine/threonine kinase 11 L homeolog antikoerper, STK11 antikoerper, stk11 antikoerper, LOC662493 antikoerper, Stk11 antikoerper, stk11.L antikoerper

Hintergrund

STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

Molekulargewicht

48636

NCBI Accession

NP_000446

UniProt

Q15831

Pathways

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt