CLASP2 Antikörper (C-Term)

Produktnummer ABIN391268

Der Kaninchen Polyklonal Anti-CLASP2-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, CLASP2 in Proben von Human zu detektieren.

Kurzübersicht für CLASP2 Antikörper (C-Term) (ABIN391268)

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLASP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB9127

Produktdetails anti-CLASP2 Antikörper

Bindungsspezifität: AA 946-975, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human CLASP2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CLASP2

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Andere Bezeichnung: CLASP2

Hintergrund: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Molekulargewicht: 141064

Gen-ID: 23122

NCBI Accession: NP_001193973, NP_055912

UniProt: O75122

Pathways: Microtubule Dynamics, Maintenance of Protein Location