Lamin B2 Antikörper (C-Term)

Produktnummer ABIN390698

Der Kaninchen Polyklonal Anti-Lamin B2-Antikörper wurde für WB validiert. Er ist geeignet, Lamin B2 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Lamin B2 Antikörper (C-Term) (ABIN390698)

Target: Lamin B2 (LMNB2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB19541

Produktdetails anti-Lamin B2 Antikörper

Bindungsspezifität: AA 476-504, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Lamin B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human Lamin B2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Lamin B2 Antikörper (ABIN390698)

Jevti?, Edens, Li, Nguyen, Chen, Levy: "Concentration-dependent Effects of Nuclear Lamins on Nuclear Size in Xenopus and Mammalian Cells." in: The Journal of biological chemistry, Vol. 290, Issue 46, pp. 27557-71, (2015) (PubMed).

Details zu Lamin B2

Target: Lamin B2 (LMNB2)

Andere Bezeichnung: Lamin B2

Hintergrund: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.

Molekulargewicht: 69948

Gen-ID: 84823

NCBI Accession: NP_116126

UniProt: Q03252

Pathways: Apoptose, Caspase Kaskade in der Apoptose