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EGFR Antikörper (pTyr1016)

Name: EGFR Antikörper (pTyr1016)
SKU: ABIN2839735
Price: 194.37 EUR
Availability: InStock

EGFR Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB11166 unconjugated

Western blot analysis of lysate from A431 cells(from left to right),untreated or treated with EGF at 100 ng/mL,using Phospho-EGFR-p Antibody (ABIN389891 and ABIN2839735) or EGFR-p Antibody. (EGFR Antikörper (pTyr1016))

Dot blot analysis of anti-EGFR B1 Phospho-specific Pab (ABIN389891 and ABIN2839735) on nitrocellulose membrane. (EGFR Antikörper (pTyr1016))

2 Abbildungen

Produktnummer ABIN2839735

Datenblatt (PDF)

Target Alle EGFR Antikörper anzeigen

EGFR (Epidermal Growth Factor Receptor (EGFR))
Bindungsspezifität
39

38

31

31

30

28

27

26

25

22

21

18

16

16

16

15

15

15

11

11

10

9

9

9

8

8

7

6

5

5

5

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3
pTyr1016
Reaktivität
761

299

287

25

25

24

20

14

8

3

2

2

1

1

1

1

1

1
Human
Wirt
581

177

14

13

5

4

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
543

248

2
Polyklonal
Konjugat
415

58

29

22

20

18

18

17

16

16

16

12

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

2

1

1

1

1

1

1
Dieser EGFR Antikörper ist unkonjugiert
Applikation
537

252

154

151

127

102

99

93

82

46

37

34

34

19

11

8

6

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Dot Blot (DB)

Homologie

M

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This EGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1016 of human EGFR.

Klon

RB11166

Isotyp

Ig Fraction

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Applikationshinweise

WB: 1:8000. DB: 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Andere Bezeichnung

EGFR (EGFR Produkte)

Hintergrund

Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. It is involved in the control of cell growth and differentiation.

Molekulargewicht

134277

Gen-ID

1956

NCBI Accession

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

Pathways

NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine