SMAD4 Antikörper (pThr277)
Kurzübersicht für SMAD4 Antikörper (pThr277) (ABIN389658)
Target
Alle SMAD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pThr277
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Homologie
- Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
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Isotyp
- Ig Fraction
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Applikationshinweise
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WB: 1:500
IHC-P: 1:10-50
IF: 1:10-50
DB: 1:500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." in: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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Andere Bezeichnung
- SMAD4
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Hintergrund
- Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
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Molekulargewicht
- 60439
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Gen-ID
- 4089
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NCBI Accession
- NP_005350
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UniProt
- Q13485
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Pathways
- Zellzyklus, Chromatin Binding, Autophagie
Target
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