CREB1 Antikörper (pSer133)
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- Target Alle CREB1 Antikörper anzeigen
- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
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Bindungsspezifität
- pSer133
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CREB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CREB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S133 of human CREB.
- Klon
- RB05198
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CREB1 Primärantikörper
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- Applikationshinweise
- WB: 1:500. WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Transgenic songbirds with suppressed or enhanced activity of CREB transcription factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 24, pp. 7599-604, (2015) (PubMed).
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Transgenic songbirds with suppressed or enhanced activity of CREB transcription factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 24, pp. 7599-604, (2015) (PubMed).
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- Target
- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
- Andere Bezeichnung
- CREB (CREB1 Produkte)
- Hintergrund
- CREB is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, (CRE), a sequence present in many viral and cellular promoters. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.
- Molekulargewicht
- 35136
- Gen-ID
- 1385
- NCBI Accession
- NP_004370, NP_604391
- UniProt
- P16220
- Pathways
- TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
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