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FNTB Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FNTB in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN389047

Kurzübersicht für FNTB Antikörper (N-Term) (ABIN389047)

Target

Alle FNTB Antikörper anzeigen
FNTB (Farnesyltransferase subunit beta (FNTB))

Reaktivität

  • 51
  • 22
  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 1
Kaninchen

Klonalität

  • 39
  • 12
Polyklonal

Konjugat

  • 23
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser FNTB Antikörper ist unkonjugiert

Applikation

  • 31
  • 25
  • 15
  • 6
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB4769-4770
  • Bindungsspezifität

    • 7
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-36, N-Term

    Homologie

    B, Rat

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This FNTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human FNTB.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:50~100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    FNTB (Farnesyltransferase subunit beta (FNTB))

    Andere Bezeichnung

    FNTB

    Hintergrund

    Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins. These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain. CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.

    Molekulargewicht

    48774

    Gen-ID

    2342

    NCBI Accession

    NP_002019

    UniProt

    P49356
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