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CD73 Antikörper (N-Term)

Dieses Anti-CD73-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD73 in IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.
Produktnummer ABIN388749

Kurzübersicht für CD73 Antikörper (N-Term) (ABIN388749)

Target

Alle CD73 (NT5E) Antikörper anzeigen
CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Reaktivität

  • 185
  • 78
  • 37
  • 19
  • 18
  • 16
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 107
  • 99
  • 22
  • 2
  • 2
  • 1
Kaninchen

Klonalität

  • 138
  • 94
  • 1
Polyklonal

Konjugat

  • 100
  • 21
  • 17
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD73 Antikörper ist unkonjugiert

Applikation

  • 153
  • 125
  • 119
  • 59
  • 46
  • 40
  • 38
  • 27
  • 15
  • 14
  • 14
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB02844
  • Bindungsspezifität

    • 16
    • 13
    • 9
    • 9
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This CD73 (NT5E) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CD73 (NT5E).

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Kim, Piao, Pak, Chung, Han, Hong, Jun, Shim, Choi, Kim: "Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction." in: Stem cells and development, Vol. 24, Issue 5, pp. 575-86, (2015) (PubMed).

    Doherty, Bai, Hanidziar, Longhi, Lawlor, Putheti, Csizmadia, Nowak, Cheifetz, Moss, Robson: "CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease." in: European journal of immunology, Vol. 42, Issue 11, pp. 3062-72, (2012) (PubMed).

    Andrade, Lopez, Noronha, Wink, Borojevic, Margis, Lenz, Battastini, Guma: "Ecto-5'-nucleotidase/CD73 knockdown increases cell migration and mRNA level of collagen I in a hepatic stellate cell line." in: Cell and tissue research, Vol. 344, Issue 2, pp. 279-86, (2011) (PubMed).

    Nadri, Soleimani, Mobarra, Amini: "Expression of dopamine-associated genes on conjunctiva stromal-derived human mesenchymal stem cells." in: Biochemical and biophysical research communications, Vol. 377, Issue 2, pp. 423-8, (2008) (PubMed).

  • Target

    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

    Andere Bezeichnung

    CD73 (NT5E)

    Hintergrund

    Ecto-5-prime-nucleotidase catalyzes conversion at neutral pH of purine 5-prime mononucleotides to nucleosides. The enzyme consists of a dimer of 2 identical 70 kD subunits tethered by a glycosyl phosphatidyl inositol moeity to the exterior plasma membrane surface. The enzyme, a marker of lymphocyte differentiation is associated in deficiency with a variety of immunodeficiency diseases. The preferred substrate is AMP. The NT5 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations.

    Molekulargewicht

    63368

    Gen-ID

    4907

    NCBI Accession

    NP_001191742, NP_002517

    UniProt

    P21589

    Pathways

    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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