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EGFR Antikörper

Name: EGFR Antikörper
SKU: ABIN387816
Price: 467.5 EUR
Availability: InStock

EGFR Reaktivität: Human WB, FACS, IHC (p) Wirt: Maus Monoclonal 51CT78-40-5 unconjugated

Western blot analysis of lysates from A431, MDA-MB-468 cell line (from left to right), using EGFR Antibody (ABIN387816 and ABIN2843905). (EGFR Antikörper)

Overlay histogram showing Hela cells stained with (ABIN387816 and ABIN2843905)(green line). (EGFR Antikörper)

FACS

Formalin-fixed and paraffin-embedded human breast carcinoma with EGFR Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (EGFR Antikörper)

IHC (p)

5 Abbildungen

Produktnummer ABIN387816

Datenblatt (PDF)

Target Alle EGFR Antikörper anzeigen

EGFR (Epidermal Growth Factor Receptor (EGFR))
Reaktivität
754

299

287

25

25

24

20

14

8

3

2

2

1

1

1

1

1

1
Human
Wirt
577

178

14

13

5

1

1
Maus
Passende Sekundärantikörper
Klonalität
539

245

2
Monoklonal
Konjugat
408

58

29

22

20

18

18

17

16

16

16

12

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

2

1

1

1

1

1

1
Dieser EGFR Antikörper ist unkonjugiert
Applikation
533

245

150

147

128

102

99

93

82

46

37

34

34

19

11

8

6

4

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

Purified His-tagged EGFR protein(Fragment) was used to produced this monoclonal antibody.

Klon

51CT78-40-5

Isotyp

IgG1 kappa

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anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR Reaktivität: Human, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:2000. IHC-P: 1:50~100. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Andere Bezeichnung

EGFR (EGFR Produkte)

Hintergrund

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Molekulargewicht

134277

Gen-ID

1956

NCBI Accession

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

Pathways

NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine