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MSH6 Antikörper

MSH6 Reaktivität: Human, Maus, Ratte, Hund WB, IP Wirt: Maus Monoclonal 44 unconjugated
Produktnummer ABIN379235
  • Target Alle MSH6 Antikörper anzeigen
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reaktivität
    • 79
    • 36
    • 30
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund
    Wirt
    • 58
    • 18
    • 3
    Maus
    Klonalität
    • 46
    • 33
    Monoklonal
    Konjugat
    • 47
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH6 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 27
    • 25
    • 22
    • 14
    • 13
    • 12
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Spezifität
    MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-based mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. cross reacts with mouse, rat and dog.
    Aufreinigung
    Purified
    Immunogen
    Synthetic human MSH6 peptide.

    Type of Immunogen: Synthetic peptide
    Klon
    44
    Isotyp
    IgG1
    Top Product
    Discover our top product MSH6 Primärantikörper
  • Applikationshinweise
    Approved: IP, WB (1:100 - 1:500)
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Buffer contains: 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Andere Bezeichnung
    MSH6 (MSH6 Produkte)
    Synonyme
    GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper
    Hintergrund
    Name/Gene ID: MSH6

    Synonyms: MSH6, GTBP, HSAP, GTMBP, MutS (E. coli) homolog 6, HMSH6, Sperm-associated protein, p160, G/T mismatch-binding protein, HNPCC5, MutS homolog 6 (E. coli), MutS-alpha 160 kDa subunit
    Gen-ID
    2956
    Pathways
    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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