CD3 Antikörper

Produktnummer ABIN376394

Der Maus Monoklonal Anti-CD3-Antikörper wurde für FACS, IP und IHC validiert. Er ist geeignet, CD3 in Proben von Human zu detektieren.

Kurzübersicht für CD3 Antikörper (ABIN376394)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Klon: UCHT1

Produktdetails anti-CD3 Antikörper

Produktmerkmale: The antibody detects: ε chain of the CD3/T cell antigen receptor complex
The monoclonal antibody UCHT1 reacts with the 20 kDa ε chain of the CD3/TCR complex.
To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform to the characteristics of a standard reference reagent.

Aufreinigung: Purified

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working Dilution:
<= 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Kommentare:

in vitro activation of T Cells

Probenmenge: 0,2 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80 % of normal peripheral blood lymphocytes and on 10-20 % of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation.

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway